Thiazide Diuretics

Considerations for providers

  • Monitor fluid intake and output, weight, bllod pressure, and electrolyte levles.
  • Watch for signs and symptoms of hypokalemia described above.
  • Consult prescriber or dietitian about potassium supplements and potassium-rich foods.
  • Monitor creatinine and BUN levels regularly. Cumulative effects of drug may occur with impaired renal function.
  • Monitor uric acid level, especially in patients with history of gout.
  • Monitor glucose level, especially in patients with diabetes.
  • Monitor elderly patients, who are especially susceptible to excessive diuresis.
  • Stop drug before parathyroid function tests.
  • In patients with hypertension, therapeutic response may be delayed several weeks.

Patient Education

  • Take drug with food to minimize stomach upset.
  • Take drug in the morning to avoid need to urinate at night.
  • Avoid sudden posture changes and rise slowly to avoid dizziness.
  • Use a sunblock to prevent photosensitivity reactions.